https://www.ceesdekker.net Secrets
https://www.ceesdekker.net Secrets
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‘Of course, that is about appropriate. I search for a Bodily comprehension of Organic methods in the base-up way. I think you might distinguish three traces of exploration in my team in the meanwhile. The first considerations chromosome framework: How does one obtain a metre-prolonged DNA polymer folded and organised in this kind of microscopic mobile? We've produced visualisation approaches that allow us to study how, as an example, SMC proteins loop DNA (online video on Youtube) in order to Develop up chromosomes.
But how do morality, the dignity from the individual, my working experience with the that means of lifestyle, follow through the movement of atoms? A purely naturalistic standpoint fails listed here; a Christian perspective, I feel, is a much more fair technique to interpret these elements of truth.’
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Deposition and atomic power microscopy of specific phthalocyanine polymers concerning nanofabricated electrodes
2010, formulated a new way (‘wedging transfer’) to manipulate nanostructures; very first report of DNA translocation by graphene nanopores; and understood hybrid nanopores by directed insertion of α-hemolysin into good-condition nanopores
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en satisfied 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde cees dekker en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
We use nanofabricated microfluidic structures to pattern spatial boundaries for bacteria and biomimetic vesicles with reconstituted protein networks which evaluate the basic position of spatial confinement with the molecular and cellular degree. Our tasks consist of the following:
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in purple, plus a 3D rendering from the movement from the DNA rod is shown.
The rotors harness Vitality from a nanoscale h2o and ion flow that is created by a static chemical or electrochemical likely gradient inside the nanopore, which can be established by way of a salt gradient or applied voltage, respectively. These synthetic nanoengines self-organize and work autonomously in physiological problems, suggesting approaches to developing Strength-transducing motors at nanoscale interfaces.
There was one particular challenge nevertheless — we didn't notice any measurable electrical conduction from The one polymer molecules. We concluded that at The one-molecule amount, conducting polymers were being actually not such fantastic conductors, which was instead disappointing. We Hence broadened our check out to try to locate much more promising molecules.
FtsZ treadmilling is important for Z-ring condensation and septal constriction initiation in bacterial mobile division
2006, to start with demonstration of molecular sorting within a lab over a chip applying biomotors; discovery of nanobubbles in strong-condition nanopores; and initially estimate of electrokinetic energy conversion within a nanofluidic channel
Permit’s to start with glimpse again for the time being once you chose to shift your target from superconductivity and nanotubes to biology at the end of the nineties.
2004, discovery of new physics in translocation of DNA as a result of nanopores; initially experimental research of ions conduction in nanofluidic channels; first electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; first biophysics characterization with the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule study of DNA translocation by a restriction-modification enzyme.